Corus CAD Patient Selection
The Corus CAD test is intended for use in patients who present with stable symptoms suggestive of obstructive CAD.
Typical symptoms suggestive of CAD may include:
- Chest discomfort, tightness, pain, or pressure
- Shortness of breath
Atypical symptoms suggestive of CAD may include:
- Tightness or pressure in the throat, jaw, shoulder, abdomen, back, or arm
- Squeezing, heaviness, or burning sensation in the upper body
- Abdominal discomfort or fullness
- Indigestion or heartburn
- Dizziness or light-headedness
- Palpitations or awareness of heartbeat
(To be suggestive of obstructive CAD*, these atypical symptoms should be concurrent with at least one CAD risk factor. Some examples of CAD risk factors include high cholesterol, hypertension, family history, smoking, post-menopausal, morbid obesity, and known non-cardiac vascular disease.)
The Corus CAD test is NOT intended for patients who:
- Have a history of obstructive CAD
- Have had a prior myocardial infarction or revascularization procedure
- Are diabetic
- Are currently taking steroids, immunosuppressive agents, or chemotherapeutic agents
For a complete description of the intended use population for the Corus CAD test, please see the Corus CAD Intended Use Statement.
* Obstructive CAD is defined as at least one atherosclerotic plaque causing ≥50% luminal diameter stenosis in a major coronary artery (≥1.5 mm lumen diameter) as determined by invasive quantitative coronary angiography or coronary computed tomography angiography (≥2.0 mm lumen diameter).